Principal investigator of the following projects:
● 2025 - 2028, Fast Scatter Correction for Straight-Line Trajectory Megavoltage Spectral CT Using Phase Space Expanded Linear Boltzmann Transport Equation, The National Key R&D Program Key Program
● 2024 - 2027, Research of High-Resolution Dual-Layer Flat-Panel-Detector Technology and Its Prototype Development, The National Key R&D Program Key Program
● 2023 - 2025, C-Arm Spectral CT Technology Innovation for Precision Brain Imaging in Interventional Diagnostic and Treatment, The National Key R&D Program Key Program
● 2021 - 2024, Oral Cone-Beam CT Spectral Imaging, The National Natural Science Foundation of China (NSFC) Key Program of Joint Fund
● 2021 - 2024, Quantitative Cone-Beam CT Imaging Using Spatial-Temporal Combined Spectral Modulation, NSFC General Program
● 2019 - 2022, Wide-coverage multi-energy CT imaging, Startup Funding for young scholar
● 2018 - 2021, Novel CT imaging for image guidance, Startup funding for new faculty
Key contributor to the following projects:
● 2022-2025, R&D of ultra-fast high-definition Stationary CT equipment for customs package inspection, The National Key R&D Program Key Program
● 2016 - 2018, Biology-guiding Radiotherapy, New product R&D, Reflexion Medical, CA, USA
● 2013 - 2016, Revolution CT GSI Xtream, New product R&D, GE Healthcare, WI, USA
● 2010 - 2013, Revolution CT, New technology R&D, GE Global Research, NY, USA
● 2010 - 2013, Cardiac CT: advanced architectures and algorithms, NIH Grant, USA
● 2008 - 2010, Efficient scatter correction, NIH Grant, USA
Selected publications
1. Yuting Chen, Yuxiang Xing, Li Zhang, Zhi Deng, and Hewei Gao*, “Energy-Threshold Bias Calculator: A Physics-Model Based Adaptive Correction Scheme for Photon-Counting CT,” IEEE Transactions on Medical Imaging, 2026.
2. Yifan Deng, N. Robert Bennett, Hewei Gao*, and Adam S. Wang, “A comparative analysis of two dual-layer flat panel detector designs and mimicking of a triple-layer flat panel detector in spectral CT,” Medical Physics, 53(2): e70338, 2026.
3. Hao Zhou, Yifan Deng, and Hewei Gao*, “Improved fast kV-switching dual-energy CBCT with a spectral modulator: System design and a feasibility study,” Medical Physics, 52(8): e18024, 2025.
4. Yingxian Xia, Li Zhang, Yuxiang Xing, Zhiqiang Chen*, and Hewei Gao*, “ComptoNet: a Compton-map guided deep learning framework for multi-scatter estimation in multi-source stationary CT,” Physics in Medicine and Biology, 70(14): 145022, 2025.
5. Yifan Deng, Hao Zhou, and Hewei Gao*, “Penumbra-effect induced spectral mixing in x-ray computed tomography: a multi-ray spectrum estimation model and subsampled weighting algorithm,” Physics in Medicine and Biology, 70(8): 085013, 2025.
6. Hao Zhou, Li Zhang, Zhilei Wang and Hewei Gao*, “Fast-kV switching and dual-layer flat panel detector enabled CBCT Joint Spectral Imaging,” Physics in Medicine and Biology, 69(11): 115005, 2024.
7. Yifan Deng, Hao Zhou, Zhilei Wang, Adam S. Wang, and Hewei Gao*, “Multi-energy blended CBCT spectral imaging and scatter-decoupled material decomposition using a spectral modulator with flying focal spot (SMFFS),” Medical Physics, 51(4): 2398-2412, 2024.
8. Zhilei Wang, Hao Zhou, Shan Gu, Yingxian Xia, Haiyue Liao, Yifan Deng, and Hewei Gao*, “Dual-Energy Head Cone-Beam CT Using a Dual-Layer Flat-Panel Detector: Hybrid Material Decomposition and a Feasibility Study,” Medical Physics, 50(11): 6762-6778, 2023.
9. Yingxian Xia, Li Zhang, Yuxiang Xing, Zhiqiang Chen*, and Hewei Gao*, “Generalized-Equiangular Geometry CT: Concept and Shift-Invariant FBP Algorithms,” Medical Physics, 50(8): 5150-5165, 2023.
10. Chengpeng Wu, Yuxiang Xing, Li Zhang*, Zhiqiang Chen, Xiaohua Zhu, Xi Zhang, and Hewei Gao*, “Fluence adaptation for contrast-based dose optimization in x-ray phase-contrast imaging,” Medical Physics, 48(10): 6106-6120, 2021.
11. Chengpeng Wu, Yuxiang Xing, Li Zhang*, Xinbin Li, Xiaohua Zhu, Xi Zhang, and Hewei Gao*, “Fourier-based interpretation and noise analysis of the moments of small-angle x-ray scattering in grating-based x-ray phase contrast imaging,” Optics Express, 29(14): 21902-21920, 2021.
12. Hewei Gao*, Tao Zhang, N. Robert Bennett, and Adam S. Wang, “Densely sampled spectral modulation for x-ray CT using a stationary modulator with flying focal spot: a conceptual and feasibility study of scatter and spectral correction,” Medical Physics, 48(4): 1557-1570, 2021.
13. Tao Zhang, Zhiqiang Chen, Hao Zhou, N. Robert Bennett, Adam S. Wang, and Hewei Gao*, “An analysis of scatter characteristics in x-ray CT spectral correction,” Physics in Medicine and Biology, 66(7): 075003, 2021.
14. Tao Zhang, Li Zhang, Zhiqiang Chen*, Yuxiang Xing, and Hewei Gao*, “Fourier Properties of Symmetric-Geometry Computed Tomography and Its Linogram Reconstruction with Neural Network,” IEEE Transactions on Medical Imaging, 39(12): 4445-4457, 2020.
15. Tao Zhang, Yuxiang Xing, Li Zhang, Xin Jin, Hewei Gao*, and Zhiqiang Chen*, “Stationary computed tomography with source and detector in linear symmetric geometry: Direct filtered backprojection reconstruction,” Medical Physics, 47(5): 2222-2236, 2020.
16. Chengpeng Wu, Li Zhang, Zhiqiang Chen, Yuxiang Xing, Xinbin Li, Xiaohua Zhu, Carolina Arboleda, Zhentian Wang, and Hewei Gao*, “The trigonometric orthogonality of phase-stepping curves in grating-based x-ray phase-contrast imaging: Integral property and its implications for noise optimization,” Medical Physics, 47(3): 1189-1198, 2020.
17. Hewei Gao*, Li Zhang, Rainer Grimmer, and Rebecca Fahrig, “Physics-based spectral compensation algorithm for X-ray CT with primary modulator,” Physics in Medicine and Biology, 64(12): 125006, 2019.
18. Hewei Gao*, Lei Zhu, and Rebecca Fahrig, “Virtual Scatter Modulation for X-ray CT Scatter Correction Using Primary Modulator,” Journal of X-ray Science and Technology, 25(6):869-885, 2017.
19. Hewei Gao*, Li Zhang*, Zhiqiang Chen, Yuxiang Xing, Hui Xue, and Jianping Cheng, “Straight-Line-Trajectory-Based X-Ray Tomographic Imaging for Security Inspections: System Design, Image Reconstruction and Preliminary Results,” IEEE Transactions on Nuclear Science, 60(5):3955-3968, 2013.
20. Hewei Gao*, Lei Zhu, and Rebecca Fahrig, “Modulator design for X-ray scatter correction using primary modulation: Material selection,” Medical Physics, 37(8):4029-4037, 2010.
21. Hewei Gao*, Rebecca Fahrig, N. Robert Bennett, Mingshan Sun, Josh Star-Lack, and Lei Zhu, “Scatter correction method for X-ray CT using primary modulation: Phantom studies,” Medical Physics, 37(2):934-946, 2010.
22. Hewei Gao*, Li Zhang*, Yuxiang Xing, Zhiqiang Chen, and Jianping Cheng, “An improved form of linogram algorithm for image reconstruction,” IEEE Transactions on Nuclear Science, 55(1):552-559, 2008.
23. Hewei Gao*, Li Zhang, Zhiqiang Chen, Yuxiang Xing, Jianping Cheng, and Yigang Yang, “Application of X-ray CT to liquid security inspection: system analysis and beam hardening correction,” Nuclear Instruments & Methods in Physics Research Section A, 579(1):395-399, 2007.
24. Hewei Gao*, Li Zhang, Yuxiang Xing, Zhiqiang Chen, Jian Zhang, and Jianping Cheng, “Volumetric imaging from a multisegment straight-line-trajectory and a practical reconstruction algorithm,” Optical Engineering, 46(7):077004, 2007.
25. Hewei Gao*, Li Zhang, Zhiqiang Chen, Yuxiang Xing, Jianping Cheng, and Zhihua Qi, “Direct filtered-backprojection-type reconstruction from a straight-line trajectory,” Optical Engineering, 46(5):057003, 2007.
26. Hewei Gao*, Li Zhang*, Zhiqiang Chen, Yuxiang Xing, and Shuanglei Li, “Beam hardening correction for middle-energy industrial computerized tomography,” IEEE Transactions on Nuclear Science, 53(5):2796-2807, 2006.
All publications in my Google Scholar academic profile:
https://scholar.google.com/citations?user=JOl6xOoAAAAJ&hl=zh-CN&oi=ao